HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Blue skies for Skyhawk: Positive news from Phase 1 trial for SKY-0515
- Buckle in: Gene therapy AMT-130 appears to slow down signs of Huntington’s disease in Phase I/II clinical trial
- Positive news from Wave Life Sciences SELECT-HD trial
- No pivot needed for PTC-518
- SURVEYOR opens the door for drugs that treat cognition
Literature
- Diagnostic Potential of Alternations of Bile Acid Profiles in the Plasma of Patients with Huntington's Disease
- Attitudes towards disclosure of familial genetic risk in a Mediterranean island population - a survey of the Maltese population
- Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas
- Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington's disease
- Epidemiology of Huntington's Disease in Latin America: A Systematic Review and Meta-Analysis
News
- Developing small Cas9 hybrids using molecular modeling | Scientific Reports - Nature
- Building bridges between cells for brain health | ScienceDaily
- Building bridges between cells for brain health | Nervous System | Head Topics
- 'Prelude' to neuromuscular disease SMA may offer chances for better treatment | Stem Cells
- 'Prelude' to neuromuscular disease SMA may offer chances for better treatment