HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Red Light, Green Light: How Huntington’s Disease Influences Genetic Traffic Lights
- Navigating the Genetic River: How Tiny Variants Could Shift the Course of Huntington’s Disease
- Excitement and Anticipation as PTC’s Huntington’s Disease Drug Clears a Major Hurdle to Sprint Home
- What’s Good for Your Heart is Good for Your Brain: New Study Links Cardiovascular Health to Brain Aging
- Assembly Line Breakdown: Protein Production Problems in Huntington’s Disease
Literature
- Smoke, Scars, and Survival: A Six-Year Analysis of Burn Mortality in a Resource-Limited Appalachian ICU
- A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA
- Doxycycline: An essential tool for Alzheimer's disease
- Coherent thalamic inputs organize head direction signal in the medial entorhinal cortex
- Visualization of autophagic structures near solid polyQ aggregates reveals how they undermine autophagy
News
- Doctors successfully treated a baby with the first ever personalized gene-editing therapy
- Study reveals impact of oft-overlooked cell in brain function - Medical Xpress
- Mini-stroke patients may experience fatigue for up to a year
- Navigating the high costs that come with Huntington's disease
- Glymphatic flow reduced in Huntington disease | Nature Reviews Neurology