HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- April 2025: This Month in Huntington’s Disease Research
- Stopping C-A-G Repeat Expansion In Its Tracks
- Ten Golden Rules for Navigating Huntington’s Disease Research News
- Roche provides an update on tominersen: What’s next for this huntingtin-lowering drug?
- Knockouts for the win: how expanding CAGs drive disease
Literature
- Finally, an understanding of Huntington's disease!
- Transient Interdomain Interactions Modulate the Monomeric Structural Ensemble and Self-Assembly of Huntingtin Exon 1
- Mitochondrial DNA editing: Key to the treatment of neurodegenerative diseases
- Repurposing Oseltamivir Against CAG Repeat Mediated Toxicity in Huntington's Disease and Spinocerebellar Ataxia Using Cellular and Drosophila Model
- Decoding the genetic blueprints of neurological disorders: disease mechanisms and breakthrough gene therapies
News
- Neurocrine Sues Zydus to Guard Ingrezza's New Sprinkle Form - Bloomberg Law News
- Biohaven gets an up to $600M investment; Prilenia, Ferrer make a deal in Europe
- To manage cognitive issues, my wife works to keep her brain busy
- Dutch biotech inks 500 million euros neurology deal | The Pharmaletter
- Prilenia, Ferrer Partner to Commercialize & Further Develop Pridopidine in Europe