HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
Literature
- Early alterations of motor learning and corticostriatal network activity in a Huntington's disease mouse model
- Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia
- Tbc1d15 knockdown in vivo alleviates α-synuclein-induced neurotoxicity by promoting autophagy.
- Interaction between histone residue H3K56 and mismatch repair protein MutSβ drives CAG repeat expansion
- Effect of chronic upregulation of endocannabinoid signaling in vivo with JZL184 on striatal synaptic plasticity and motor learning in YAC128 Huntington disease mice
News
- Team Hope Walk at Wantagh Park raises funds for Huntington's disease
- Doctor Odyssey season 1, episode 3 recap and review: "Plastic Surgery Week"
- Podcast: Excellence in Huntington's Disease Care - UConn Today
- Alterity Therapeutics Limited American Depositary Shares - ATHE STOCK NEWS
- The Huskies Take Foxborough: Marching Band to Play During NFL Game - UConn Today