Elevate HD-Related
Scientific Research
Promote Scientific Collaboration
Access to Unique Applications and Tools
Disseminate Data
HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Latest news and publications from around the HD Ecosystem
HDBuzz
- Another tool in the box: Creation of a molecular “dimmer switch” advances gene editing
- Unpacking recent gene therapy press
- Does blood hold the key to testing treatments earlier in HD patients?
- A first for CRISPR gene editing could have wider applications for human disease
- Scientists identify precisely how pridopidine works in models of Huntington’s disease
Literature
- A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans [NCBI]
- Nuclei Isolation and Super-Resolution Structured Illumination Microscopy for Examining Nucleoporin Alterations in Human Neurodegeneration [NCBI]
- Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans [NCBI]
- Amplification of neurotoxic HTTex1 assemblies in human neurons [NCBI]
- Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson's Disease Dementia [NCBI]
