HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
Literature
- Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
- Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells <em>via</em> circRNAs as a potential therapeutic approach for neurodegenerative diseases
- Using the LASSI-L to Detect Robust Interference Effects in Premanifest Huntington Disease
- Modeling Huntington disease through microRNA-mediated neural reprogramming identifies age-associated autophagy dysfunction driving the onset of neurodegeneration
- Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus
News
- Novartis confirms it has stopped development of experimental Huntington's drug
- Novartis cans branaplam after seeing Huntington's safety signal - Fierce Biotech
- Novartis trims its pipeline - Evaluate Pharma
- Marie CAMPBELL Obituary (2023) - King's Lynn, Norfolk - Legacy.com
- Spark Therapeutics Enters Into Strategic Collaboration with Neurochase - MyChesCo