HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Giving Thanks to the Huntington's Disease Family Community for Advancing Research
- Self-determination on the HD journey: the role of Advanced Care Planning
- 2024 HDBuzz Prize: Beyond nerve cells – who are the other players in the HD brain?
- Face-to-face: Huntington’s disease families are heard by the FDA
- The dust has settled: Sage’s dalzanemdor won’t advance for cognitive impairment
Literature
- Cognitive engagement may slow clinical progression and brain atrophy in Huntington's disease
- CRISPR/Cas9-induced double-strand breaks in the huntingtin locus lead to CAG repeat contraction through DNA end resection and homology-mediated repair
- Evidence-Based Review on Symptomatic Management of Huntington's Disease
- beta-Blocker Use and Delayed Onset and Progression of Huntington Disease
- Protective Effects of Antcin H Isolated from Antrodia cinnamomea Against Neuroinflammation in Huntington's Disease via NLRP3 Inflammasome Inhibition
News
- Cognitive engagement may slow clinical progression and brain atrophy in Huntington's disease
- New therapy for Huntington's disease 'may slow disease progression' | Shropshire Star
- New therapy for Huntington's disease 'may slow disease progression' - Ireland Live
- With Trump on the way, advocates look to states to pick up medical debt fight
- New therapy for Huntington's disease 'may slow disease progression' | The Independent