HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Huntington’s Disease Therapeutics Conference 2026 – Day 3
- Huntington’s Disease Therapeutics Conference 2026 – Day 2
- Huntington’s Disease Therapeutics Conference 2026 – Day 1
- Australia Opens The Door for SKY-0515: Skyhawk Seeks Provisional Approval for Its Oral HD Drug
- The road ahead for uniQure: FDA says more data needed for AMT-130 gene therapy
Literature
- Huntington's disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion
- Surface-Engineered Precision Nano-Systems for Targeted Treatment of Huntington's Disease: A Review of Recent Advancements
- Silmitasertib, an FDA-designated orphan CK2 inhibitor, ameliorates neuropathology and motor dysfunction in a Huntington's disease mouse model
- Electroconvulsive therapy in a patient with Huntington's disease and depression: a case-report
- Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin
News
- Allie LaForce inks multiyear extension with TNT Sports
- Keep up the momentum for gene therapies | Nature Medicine
- Literary Society of the Desert hosts neuroscientist author Lisa Genova
- Why GH Fans Think Britt & Jason Are Leaving Permanently - ComingSoon.net
- Why uniQure (QURE) Is Up 59.1% After FDA Oversight Shift and AMT-130 Analyst Upgrades




