HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Latest news and publications from around the HD Ecosystem
HDBuzz
- Sad news from the SIGNAL study: pepinemab does not influence HD symptoms
- When genes are unstable: targeting somatic instability in HD
- Working as a team: Changes in brain development mean some brain regions may be slacking off
- Caution urged for the use of gene-editing technology CRISPR
- HD and Histamines: Targeting Hybrid Receptors to Quiet Stressful Brain Talk
Literature
- Shared and oppositely regulated transcriptomic signatures in Huntington's disease and brain ischemia confirm known and unveil novel potential neuroprotective genes [NCBI]
- Human Huntington's disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species [NCBI]
- Understanding the Multiple Role of Mitochondria in Parkinson's Disease and Related Disorders: Lesson From Genetics and Protein-Interaction Network [NCBI]
- svReg: Structural varying-coefficient regression to differentiate how regional brain atrophy affects motor impairment for Huntington disease severity groups [NCBI]
- Molecular Components of Store-Operated Calcium Channels in the Regulation of Neural Stem Cell Physiology, Neurogenesis, and the Pathology of Huntington's Disease [NCBI]
News
- Can Ionis Pharmaceuticals Stock See A Rebound After Falling 28% YTD?
- Don't Believe Everything You Read (Except This Column)
- Don't Believe Everything You Read (Except This Column)
- Long-serving nursing couple to retire and set up care home in native country
- Trends of Invasive Brain Monitoring Device Market Reviewed for with Industry Outlook to 2024